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Ten clinical trials to watch through the end of the year

Readouts in Alzheimer's disease, heart failure and pancreatic cancer will shape pipelines and share prices over the coming months.

By Lena FischerPublished · Updated Oct. 2, 2026 · 1 min read

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A technician handles sample tubes.
A technician handles sample tubes.Photograph: Unsplash

Late-stage results are the events that most reliably move this industry, and the back half of the year is unusually dense with them. We are tracking ten.

Sponsor Area Phase Expected
Marrow Peak Multiple myeloma 3 October
Ionwell Obesity, muscle preservation 2b October
Brightwater Oncology Pancreatic cancer 3 November
Nordlicht Pharma Heart failure 3 November
Sundari Life Sciences Early Alzheimer's disease 3 November
Palisade Rx Chronic kidney disease 3 December
Tessaly Genomics Sickle cell disease 1/2 December
Quillon Biosciences Crohn's disease 3 December
Halvern Therapeutics Lung cancer, first line 3 December
Corvane Bio Rare metabolic disorder 3 Early 2027

The ones that matter most

Sundari in Alzheimer's. The company's oral drug targets inflammation rather than amyloid. A positive result would be the first for that approach in a pivotal trial. Most analysts put the odds below one in four.

Brightwater in pancreatic cancer. An interim look in the spring allowed the study to continue unchanged, which investors read as mildly encouraging. Median survival in the control arm is expected to be about eleven months.

Nordlicht in heart failure. The trial enrolled 6,200 patients and is the largest on this list. It is designed to show a reduction in hospitalizations and cardiovascular death.

We will update this page as results arrive.

Lena Fischer

Editor, Clinical Research

Lena edits the site's trial coverage and writes the weekly data column. She trained as a biostatistician and has reported on clinical research for more than a decade.